(a) Structure and function
of cell andits organelles(nucleus, plasma membrane, mitochondria, Golgi
bodies, endoplasmic reticulum, ribosomes and Iysosomes), cell division
(mitosis and meiosis), mitotic spindle and mitotic apparatus, chromosome
movement.
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(b) Watson-Crick model of
DNA, replication of DNA, protein synthesis, transcription and
transcription factors.
II.
Genetics
a) Gene structure and
functions; genetic code.
(b) Sex chromosomes and sex
determination in Drosophilla, nematodes and man.
(c) Mendel's laws of
inheritance, recombination, linkage, linkage-maps, multiple alleles,
cistron concept; genetics of blood groups.
(d) Mutations and
mutagenesis : radiation and chemical.
(e) Cloning technology,
plasmids and cosmids as vectors, transgenics, transposons, DNA sequence
cloning and whole animal cloning (Principles and methodology).
(f) Regulation and gene
expression in pro-and eu-karyotes.
(g) Signal transduction;
pedigree-analysis; congenital diseases in man.
(h) Human genome mapping;
DNA finger-printing.
III.
Evolution
(a) Origin of life
(b) Natural selection, role
of mutation in evolution, mimicry, variation, isolation, speciation.
(c) Fossils and
fossilization; evolution of horse, elephant and man.
(d) Hardy-Weinberg Law,
causes of change in gene frequency.
(e) Continental drift and
distribution of animals.
IV.
Systematics
(a) Zoological
nomenclature; international code; cladistics.
Section-B
I.
Biochemistry
(a) Structure and role of
carbohydrates, fats, lipids, proteins, aminoacids, nucleic acids;
saturated and unsaturated fattyacids, cholesterol.
(b) Glycolysis and Krebs
cycle, oxidation and reduction, oxidative phosphorylation; energy
conservation and release, ATP, cyclic AMP-its structure and role.
(c) Hormone classification
(steroid and peptide hormones), biosynthesis and function.
(d) Enzymes : types and
mechanisms of action; immunoglobulin and immunity; vitamins and
co-enzymes.
(e) Bioenergetics.
II Physiology (with
special refernece ot mammals)
(a) Composition and
constitutents of blood; blood groups and Rh factor in man; coagulation,
factors and mechanism of coagulation; acid-base balance, thermo
regulation.
(b) Oxygen and carbon
dioxide transport; haemoglobin : constitutents and role in regulation.
(c) Nutritive requirements;
role of salivary glands, liver, pancreas and intestinal glands in
digestion and absorption.
(d) Excretory products;
nephron and regulation of urine formation; osmoregulation.
(e) Types of muscles,
mechanism of contraction of skeletal muscles.
(f) Neuron, nerve
impulse-its conduction and synaptic transmission; neurotransmitters.
(g) Vision, hearing and
olfaction in man.
(h) Mechanism of hormone
action.
(i) Physiology of
reproduction, role of hormones and phermones.
III.
Developmental Biology
(a) Differentiation from
gamete to neurula stage; dedifferentiation; metaplasia, induction,
morphogenesis and morphogen; fate maps of gastrulae in frog and chick;
organogenesis of eye and heart, placenation in mammals.
(b) Role of cytoplasm in
and genetic control of development; cell lineage; causation of
metamorphosis in frog and insects; paedogenesia and neoteny; growth,
degrowth and cell death; ageing; blastogenesis; regeneration;
teratogenesis; neoplasia.
(c) Invasiveness of
placenta; in vitro fertilization; embryo transfer, cloning.